Nahrendorf Lab

Libby P, Nahrendorf M, Swirski FK

Reply: The Networks Between the Sympathetic Nervous System and Immune System in Atherosclerosis.
J Am Coll Cardiol. 2016;68(4):432 - PMID: 27443446 - DOI: 10.1016/j.jacc.2016.05.017

Sager HB, Nahrendorf M

Inflammation: a trigger for acute coronary syndrome.
Q J Nucl Med Mol Imaging. 2016;60(3):185-93 - PMID: 27273431

Pinciroli R, Mietto C, Piriyapatsom A, Chenelle CT, Thomas JG, Pirrone M, Bry L, Wojtkiewicz GR, Nahrendorf MP, Kacmarek RM, Berra L

Endotracheal Tubes Cleaned With a Novel Mechanism for Secretion Removal: A Randomized Controlled Clinical Study.
Respir Care. 2016;61(11):1431-1439 - PMID: 27460104 - DOI: 10.4187/respcare.04363

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.
Nat Med. 2016;22(8):945-51 - PMID: 27428900 - PMCID: PMC4957133 - DOI: 10.1038/nm.4146

Ryu WS, Schellingerhout D, Jeong SW, Nahrendorf M, Kim DE

Association between Serum Lipid Profiles and Early Neurological Deterioration in Acute Ischemic Stroke.
J Stroke Cerebrovasc Dis. 2016;25(8):2024-30 - PMID: 27256172 - DOI: 10.1016/j.jstrokecerebrovasdis.2016.05.009

Libby P, Nahrendorf M, Swirski FK

Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum".
J Am Coll Cardiol. 2016;67(9):1091-1103 - PMID: 26940931 - PMCID: PMC4779182 - DOI: 10.1016/j.jacc.2015.12.048

Calcagno C, Mulder WJ, Nahrendorf M, Fayad ZA

Systems Biology and Noninvasive Imaging of Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2016;36(2):e1-8 - PMID: 26819466 - PMCID: PMC4861402 - DOI: 10.1161/ATVBAHA.115.306350

Ali M, Pulli B, Courties G, Tricot B, Sebas M, Iwamoto Y, Hilgendorf I, Schob S, Dong A, Zheng W, Skoura A, Kalgukar A, Cortes C, Ruggeri R, Swirski FK, Nahrendorf M, Buckbinder L, Chen JW

Myeloperoxidase Inhibition Improves Ventricular Function and Remodeling After Experimental Myocardial Infarction.
JACC Basic Transl Sci. 2016;1(7):633-643 - PMID: 30167547 - PMCID: PMC6113523 - DOI: 10.1016/j.jacbts.2016.09.004

Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ

Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Proc Natl Acad Sci U S A. 2016;113(44):E6731-E6740 - PMID: 27791119 - PMCID: PMC5098679 - DOI: 10.1073/pnas.1609629113

Kim J, Park JE, Nahrendorf M, Kim DE

Direct Thrombus Imaging in Stroke.
J Stroke. 2016;18(3):286-296 - PMID: 27733029 - PMCID: PMC5066439 - DOI: 10.5853/jos.2016.00906

Swirski FK, Nahrendorf M, Libby P

Mechanisms of Myeloid Cell Modulation of Atherosclerosis.
Microbiol Spectr. 2016;4(4):ePub - PMID: 27726819 - DOI: 10.1128/microbiolspec.MCHD-0026-2015

Swirski FK, Nahrendorf M

Bone Marrow Takes Center Stage in Cardiovascular Disease.
Circ Res. 2016;119(6):701-3 - PMID: 27587406 - PMCID: PMC5012290 - DOI: 10.1161/CIRCRESAHA.116.309584

Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M

E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2016;36(9):1802-8 - PMID: 27470513 - PMCID: PMC5001901 - DOI: 10.1161/ATVBAHA.116.307519

Nahrendorf M, Swirski FK

Abandoning M1/M2 for a Network Model of Macrophage Function.
Circ Res. 2016;119(3):414-7 - PMID: 27458196 - PMCID: PMC4965179 - DOI: 10.1161/CIRCRESAHA.116.309194

Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circ Res. 2016;119(7):853-64 - PMID: 27444755 - PMCID: PMC5378496 - DOI: 10.1161/CIRCRESAHA.116.309001

Rischpler C, Dirschinger RJ, Nekolla SG, Kossmann H, Nicolosi S, Hanus F, van Marwick S, Kunze KP, Meinicke A, Götze K, Kastrati A, Langwieser N, Ibrahim T, Nahrendorf M, Schwaiger M, Laugwitz KL

Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome.
Circ Cardiovasc Imaging. 2016;9(4):e004316 - PMID: 27056601 - PMCID: PMC4826716 - DOI: 10.1161/CIRCIMAGING.115.004316

Davis RW, Brannen AD, Hossain MJ, Monsma S, Bock PE, Nahrendorf M, Mead D, Lodes M, Liles MR, Panizzi P

Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains.
BMC Genomics. 2016;17:179 - PMID: 26940863 - PMCID: PMC4778325 - DOI: 10.1186/s12864-016-2433-8

Swirski FK, Robbins CS, Nahrendorf M

Development and Function of Arterial and Cardiac Macrophages.
Trends Immunol. 2016;37(1):32-40 - PMID: 26748179 - PMCID: PMC4706986 - DOI: 10.1016/j.it.2015.11.004

Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F

Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Circ Heart Fail. 2016;9(1):e002724 - PMID: 26721917 - PMCID: PMC4698901 - DOI: 10.1161/CIRCHEARTFAILURE.115.002724

Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.
Sci Transl Med. 2016;8(342):342ra80 - PMID: 27280687 - PMCID: PMC5125383 - DOI: 10.1126/scitranslmed.aaf1435

Nahrendorf M, Swirski FK

Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction?
Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592 - DOI: 10.1093/eurheartj/ehv453

Nahrendorf M, Swirski FK

PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction.
JACC Cardiovasc Imaging. 2015;8(12):1427-1429 - PMID: 26699111 - DOI: 10.1016/j.jcmg.2015.10.004

Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M

Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.
Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135 - DOI: 10.1038/ncomms9803

Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A

Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.
Int J Cardiovasc Imaging. 2015;32(1):113-9 - PMID: 26411879 - PMCID: PMC4730873 - DOI: 10.1007/s10554-015-0766-z

Ye YX, Calcagno C, Binderup T, Courties G, Keliher EJ, Wojtkiewicz GR, Iwamoto Y, Tang J, Pérez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjaer A, Mulder WJ, Nahrendorf M

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - DOI: 10.1161/CIRCRESAHA.115.307024

Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616 - DOI: 10.1126/sciadv.1400223

Nahrendorf M, Swirski FK

Immunology. Neutrophil-macrophage communication in inflammation and atherosclerosis.
Science. 2015;349(6245):237-8 - PMID: 26185231 - DOI: 10.1126/science.aac7801

Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA

Imaging systemic inflammatory networks in ischemic heart disease.
J Am Coll Cardiol. 2015;65(15):1583-91 - PMID: 25881940 - PMCID: PMC4401833 - DOI: 10.1016/j.jacc.2015.02.034

Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978 - DOI: 10.1016/j.cmet.2015.03.006

Hulsmans M, Sam F, Nahrendorf M

Monocyte and macrophage contributions to cardiac remodeling.
J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552 - DOI: 10.1016/j.yjmcc.2015.11.015

Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A

Splenic metabolic activity predicts risk of future cardiovascular events: demonstration of a cardiosplenic axis in humans.
JACC Cardiovasc Imaging. 2015;8(2):121-30 - PMID: 25577441 - PMCID: PMC6855915 - DOI: 10.1016/j.jcmg.2014.10.009

Weissleder R, Nahrendorf M

Advancing biomedical imaging.
Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297 - DOI: 10.1073/pnas.1508524112

Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795 - DOI: 10.1161/CIRCULATIONAHA.115.016160

Nahrendorf M, Dutta P

Targeting splenic hematopoietic stem cells in cardiovascular disease.
Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955 - DOI: 10.18632/oncotarget.4918

Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G

Detecting the vulnerable plaque in patients.
J Intern Med. 2015;278(5):520-30 - PMID: 26306911 - DOI: 10.1111/joim.12414

He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK

Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849 - DOI: 10.1161/CIRCHEARTFAILURE.115.002334

Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499 - DOI: 10.7150/thno.11679

Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P

In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model.
Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872 - DOI: 10.1007/s11307-015-0856-2

Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283 - DOI: 10.1084/jem.20141642

Dutta P, Nahrendorf M

Monocytes in myocardial infarction.
Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536 - DOI: 10.1161/ATVBAHA.114.304652

Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK

Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Science. 2015;347(6227):1260-5 - PMID: 25766237 - PMCID: PMC4376966 - DOI: 10.1126/science.aaa4268

Nahrendorf M, Swirski FK

Lifestyle effects on hematopoiesis and atherosclerosis.
Circ Res. 2015;116(5):884-94 - PMID: 25722442 - PMCID: PMC4347940 - DOI: 10.1161/CIRCRESAHA.116.303550

Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M

Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.
Cell Stem Cell. 2015;16(5):477-87 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008

Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649 - DOI: 10.1084/jem.20131471

Courties G, Herisson F, Sager HB, Heidt T, Ye Y, Wei Y, Sun Y, Severe N, Dutta P, Scharff J, Scadden DT, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M

Ischemic stroke activates hematopoietic bone marrow stem cells.
Circ Res. 2014;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - DOI: 10.1161/CIRCRESAHA.116.305207

Dutta P, Nahrendorf M

Regulation and consequences of monocytosis.
Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415 - DOI: 10.1111/imr.12219

Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AKR, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Schroeder A, Panigrahy D, Kotelianski V, Langer R, Anderson DG

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
Nat Nanotechnol. 2014;9(8):648-655 - PMID: 24813696 - PMCID: PMC4207430 - DOI: 10.1038/nnano.2014.84

Pittet MJ, Nahrendorf M, Swirski FK

The journey from stem cell to macrophage.
Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243 - DOI: 10.1111/nyas.12393

Panizzi P, Stone JR, Nahrendorf M

Endocarditis and molecular imaging.
J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242 - DOI: 10.1007/s12350-014-9902-8

Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M

Silencing of CCR2 in myocarditis.
Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633 - DOI: 10.1093/eurheartj/ehu225

Courties G, Moskowitz MA, Nahrendorf M

The innate immune system after ischemic injury: lessons to be learned from the heart and brain.
JAMA Neurol. 2014;71(2):233-6 - PMID: 24296962 - PMCID: PMC3946050 - DOI: 10.1001/jamaneurol.2013.5026

Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L

Tracheal tube obstruction in mechanically ventilated patients assessed by high-resolution computed tomography.
Anesthesiology. 2014;121(6):1226-35 - PMID: 25254903 - DOI: 10.1097/ALN.0000000000000455

Nahrendorf M, Swirski FK

Imaging systemic inflammation in patients with acute myocardial infarction.
Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235 - DOI: 10.1161/CIRCIMAGING.114.002410

Swirski FK, Nahrendorf M

Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions?
Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538 - DOI: 10.1161/CIRCRESAHA.114.304925

Taqueti VR, Nahrendorf M, Di Carli MF

Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma.
J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239 - DOI: 10.1016/j.jacc.2014.07.004

Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P

Increased microvascularization and vessel permeability associate with active inflammation in human atheromata.
Circ Cardiovasc Imaging. 2014;7(6):920-9 - PMID: 25170063 - PMCID: PMC4237630 - DOI: 10.1161/CIRCIMAGING.114.002113

Nahrendorf M, Swirski FK

Regulating repair: regulatory T cells in myocardial infarction.
Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354 - DOI: 10.1161/CIRCRESAHA.114.304295

Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M

Imaging and nanomedicine in inflammatory atherosclerosis.
Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - DOI: 10.1126/scitranslmed.3005101

Heidt T, Courties G, Dutta P, Sager HB, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M

Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction.
Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439 - DOI: 10.1161/CIRCRESAHA.115.303567

Hilgendorf I, Gerhardt LM, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium.
Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349 - DOI: 10.1161/CIRCRESAHA.114.303204

Nahrendorf M, Swirski FK

Fluorescent leukocytes enter plaque on the microscope stage.
Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183 - DOI: 10.1161/CIRCRESAHA.114.303520

Frantz S, Nahrendorf M

Cardiac macrophages and their role in ischaemic heart disease.
Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449 - DOI: 10.1093/cvr/cvu025

Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655 - DOI: 10.1161/CIRCULATIONAHA.113.006381

Weissleder R, Nahrendorf M, Pittet MJ

Imaging macrophages with nanoparticles.
Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - DOI: 10.1038/nmat3780

Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.
Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802 - DOI: 10.1038/ncomms4065

Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M

Chronic variable stress activates hematopoietic stem cells.
Nat Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061 - DOI: 10.1038/nm.3589

van der Laan AM, Ter Horst EN, Delewi R, Begieneman MP, Krijnen PA, Hirsch A, Lavaei M, Nahrendorf M, Horrevoets AJ, Niessen HW, Piek JJ

Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir.
Eur Heart J. 2013;35(6):376-85 - PMID: 23966310 - PMCID: PMC3916776 - DOI: 10.1093/eurheartj/eht331

Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M

Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice.
Circulation. 2013;127(20):2038-46 - PMID: 23616627 - PMCID: PMC3661714 - DOI: 10.1161/CIRCULATIONAHA.112.000116

Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
J Am Coll Cardiol. 2013;63(15):1556-66 - PMID: 24361318 - PMCID: PMC3992176 - DOI: 10.1016/j.jacc.2013.11.023

Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R

Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging.
Biomed Opt Express. 2013;4(10):2095-106 - PMID: 24156067 - PMCID: PMC3799669 - DOI: 10.1364/BOE.4.002095

Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.
Nat Biotechnol. 2013;31(10):898-907 - PMID: 24013197 - PMCID: PMC4058317 - DOI: 10.1038/nbt.2682

Swirski FK, Nahrendorf M

Macrophage-stem cell crosstalk after myocardial infarction.
J Am Coll Cardiol. 2013;62(20):1902-4 - PMID: 23973700 - DOI: 10.1016/j.jacc.2013.07.058

Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, Figueiredo JL, Gorbatov R, Sukhova GK, Gerhardt LM, Smyth D, Zavitz CC, Shikatani EA, Parsons M, van Rooijen N, Lin HY, Husain M, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Local proliferation dominates lesional macrophage accumulation in atherosclerosis.
Nat Med. 2013;19(9):1166-72 - PMID: 23933982 - PMCID: PMC3769444 - DOI: 10.1038/nm.3258

Lameijer MA, Tang J, Nahrendorf M, Beelen RH, Mulder WJ

Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.
Expert Rev Mol Diagn. 2013;13(6):567-80 - PMID: 23895127 - PMCID: PMC4110962 - DOI: 10.1586/14737159.2013.819216

Libby P, Nahrendorf M, Swirski FK

Monocyte heterogeneity in cardiovascular disease.
Semin Immunopathol. 2013;35(5):553-62 - PMID: 23839097 - PMCID: PMC3755757 - DOI: 10.1007/s00281-013-0387-3

Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M

Nanoparticle PET-CT detects rejection and immunomodulation in cardiac allografts.
Circ Cardiovasc Imaging. 2013;6(4):568-73 - PMID: 23771986 - PMCID: PMC3734553 - DOI: 10.1161/CIRCIMAGING.113.000481

Nahrendorf M, Swirski FK

Monocyte and macrophage heterogeneity in the heart.
Circ Res. 2013;112(12):1624-33 - PMID: 23743228 - PMCID: PMC3753681 - DOI: 10.1161/CIRCRESAHA.113.300890

Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE

Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.
Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276 - DOI: 10.1161/CIRCIMAGING.112.000074

Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH

Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts.
Circ Res. 2013;112(6):891-9 - PMID: 23392842 - PMCID: PMC3834270 - DOI: 10.1161/CIRCRESAHA.111.300484

Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ

Angiotensin II drives the production of tumor-promoting macrophages.
Immunity. 2013;38(2):296-308 - PMID: 23333075 - PMCID: PMC3582771 - DOI: 10.1016/j.immuni.2012.10.015

Majmudar MD, Yoo J, Keliher EJ, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M

Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques.
Circ Res. 2013;112(5):755-61 - PMID: 23300273 - PMCID: PMC3586287 - DOI: 10.1161/CIRCRESAHA.111.300576

van der Laan AM, Nahrendorf M, Piek JJ

Republished: healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Postgrad Med J. 2013;89(1047):52-8 - PMID: 23257717 - DOI: 10.1136/postgradmedj-2012-301623rep

Swirski FK, Nahrendorf M

Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure.
Science. 2013;339(6116):161-6 - PMID: 23307733 - PMCID: PMC3891792 - DOI: 10.1126/science.1230719

Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Mol Ther Nucleic Acids. 2012;1(1):e4 - PMID: 23344621 - PMCID: PMC3381593 - DOI: 10.1038/mtna.2011.3

Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, MacDougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG

Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589 - DOI: 10.1073/pnas.1217972110

Courties G, Nahrendorf M

Enlightened stem cells in the heart: more efficient and safer reporter gene imaging.
Circ Res. 2012;111(12):1486-7 - PMID: 23223928 - DOI: 10.1161/CIRCRESAHA.112.280982

Swirski FK, Nahrendorf M

Imaging macrophage development and fate in atherosclerosis and myocardial infarction.
Immunol Cell Biol. 2012;91(4):297-303 - PMID: 23207281 - PMCID: PMC3875224 - DOI: 10.1038/icb.2012.72

Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ

Origins of tumor-associated macrophages and neutrophils.
Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379 - DOI: 10.1073/pnas.1113744109

Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA

Programming human pluripotent stem cells into white and brown adipocytes.
Nat Cell Biol. 2012;14(2):209-19 - PMID: 22246346 - PMCID: PMC3385947 - DOI: 10.1038/ncb2411

Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J

Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.
FASEB J. 2012;27(3):871-81 - PMID: 23159933 - DOI: 10.1096/fj.12-214049

Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M

Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway.
JACC Cardiovasc Imaging. 2012;5(11):1127-38 - PMID: 23153913 - PMCID: PMC3502014 - DOI: 10.1016/j.jcmg.2012.01.025

Sosnovik DE, Nahrendorf M

Cells and iron oxide nanoparticles on the move: magnetic resonance imaging of monocyte homing and myocardial inflammation in patients with ST-elevation myocardial infarction.
Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959 - DOI: 10.1161/CIRCIMAGING.112.978932

Nahrendorf M

Macrophages in the infarct: fiery friends or friendly fire?
J Mol Cell Cardiol. 2012;53(5):591-2 - PMID: 22975014 - DOI: 10.1016/j.yjmcc.2012.09.001

Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivoravov M, Sbarbati A, Nahrendorf M, Weissleder R

Real-time in vivo imaging of the beating mouse heart at microscopic resolution.
Nat Commun. 2012;3:1054 - PMID: 22968700 - PMCID: PMC3622400 - DOI: 10.1038/ncomms2060

van der Laan AM, Nahrendorf M, Piek JJ

Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Heart. 2012;98(18):1384-90 - PMID: 22904145 - DOI: 10.1136/heartjnl-2012-301623

Sosnovik DE, Nahrendorf M, Caravan P

Science to practice: how will myocardial inflammation be imaged with MR imaging?
Radiology. 2012;264(2):309-11 - PMID: 22821689 - PMCID: PMC6939999 - DOI: 10.1148/radiol.12121094

Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips JA, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM

Tracking mesenchymal stem cells with iron oxide nanoparticle loaded poly(lactide-co-glycolide) microparticles.
Nano Lett. 2012;12(8):4131-9 - PMID: 22769232 - PMCID: PMC3552518 - DOI: 10.1021/nl301658q

Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AM, Niessen HW, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M

Myocardial infarction accelerates atherosclerosis.
Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326 - DOI: 10.1038/nature11260

Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Nat Nanotechnol. 2012;7(6):389-93 - PMID: 22659608 - PMCID: PMC3898745 - DOI: 10.1038/nnano.2012.73

Degousee N, Simpson J, Fazel S, Scholich K, Angoulvant D, Angioni C, Schmidt H, Korotkova M, Stefanski E, Wang XH, Lindsay TF, Ofek E, Pierre S, Butany J, Jakobsson PJ, Keating A, Li RK, Nahrendorf M, Geisslinger G, Backx PH, Rubin BB

Lack of microsomal prostaglandin E(2) synthase-1 in bone marrow-derived myeloid cells impairs left ventricular function and increases mortality after acute myocardial infarction.
Circulation. 2012;125(23):2904-13 - PMID: 22589381 - DOI: 10.1161/CIRCULATIONAHA.112.099754

Vinegoni C, Fumene Feruglio P, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R

Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography.
PLoS One. 2012;7(4):e34427 - PMID: 22509302 - PMCID: PMC3324534 - DOI: 10.1371/journal.pone.0034427

Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG

Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics.
Biomaterials. 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278 - DOI: 10.1016/j.biomaterials.2012.03.065

Majmudar MD, Nahrendorf M

Cardiovascular molecular imaging: the road ahead.
J Nucl Med. 2012;53(5):673-6 - PMID: 22492729 - PMCID: PMC3744821 - DOI: 10.2967/jnumed.111.099838

Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier R, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ

Regulation of monocyte functional heterogeneity by miR-146a and Relb.
Cell Rep. 2012;1(4):317-24 - PMID: 22545247 - PMCID: PMC3334310 - DOI: 10.1016/j.celrep.2012.02.009

Nahrendorf M, McCarthy JR, Libby P

Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque.
Circ Res. 2012;110(7):902-3 - PMID: 22461358 - DOI: 10.1161/CIRCRESAHA.112.267260

Swirski FK, Nahrendorf M, Libby P

The ins and outs of inflammatory cells in atheromata.
Cell Metab. 2012;15(2):135-6 - PMID: 22326216 - DOI: 10.1016/j.cmet.2012.01.012

Rauch PJ, Chudnovskiy A, Robbins CS, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK

Innate response activator B cells protect against microbial sepsis.
Science. 2012;335(6068):597-601 - PMID: 22245738 - PMCID: PMC3279743 - DOI: 10.1126/science.1215173

Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M

Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis.
J Exp Med. 2012;209(1):123-37 - PMID: 22213805 - PMCID: PMC3260875 - DOI: 10.1084/jem.20111009

Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MP, Niessen HW, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M

PET/MRI of inflammation in myocardial infarction.
J Am Coll Cardiol. 2012;59(2):153-63 - PMID: 22222080 - PMCID: PMC3257823 - DOI: 10.1016/j.jacc.2011.08.066

Su HS, Nahrendorf M, Panizzi P, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW

Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase.
Radiology. 2011;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672 - DOI: 10.1148/radiol.11110040

Panizzi P, Nahrendorf M, Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R

In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation.
Nat Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740 - DOI: 10.1038/nm.2423

Leuschner F, Nahrendorf M

Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic.
Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - DOI: 10.1161/CIRCRESAHA.110.232678

Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM

Nanoparticle-based monitoring of cell therapy.
Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527 - DOI: 10.1088/0957-4484/22/49/494001

Shon SM, Park JH, Nahrendorf M, Schellingerhout D, Kim JY, Kang BT, Jeong SW, Kim EJ, Ryu JH, Kim K, Kwon IC, Lee DK, Lee MM, Kim DE

Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.
Atherosclerosis. 2011;216(1):67-73 - PMID: 21334624 - DOI: 10.1016/j.atherosclerosis.2011.01.036

Keliher EJ, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet MJ, Weissleder R

89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging.
Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512 - DOI: 10.1021/bc200405d

Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D

Direct thrombus imaging as a means to control the variability of mouse embolic infarct models: the role of optical molecular imaging.
Stroke. 2011;42(12):3566-73 - PMID: 22020025 - DOI: 10.1161/STROKEAHA.111.629428

Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M

Therapeutic siRNA silencing in inflammatory monocytes in mice.
Nat Biotechnol. 2011;29(11):1005-10 - PMID: 21983520 - PMCID: PMC3212614 - DOI: 10.1038/nbt.1989

Nahrendorf M, Sosnovik DE

Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?
Radiology. 2011;260(2):309-10 - PMID: 21778448 - DOI: 10.1148/radiol.11111017

Nahrendorf M

Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity.
Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180 - DOI: 10.1161/CIRCIMAGING.111.966671

Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R

Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging.
Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488 - DOI: 10.1161/CIRCULATIONAHA.110.000943

Laha M, Panizzi P, Nahrendorf M, Bock PE

Engineering streptokinase for generation of active site-labeled plasminogen analogs.
Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107 - DOI: 10.1016/j.ab.2011.04.025

Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O

Feasibility of contrast-enhanced and nonenhanced MRI for intraprocedural and postprocedural lesion visualization in interventional electrophysiology: animal studies and early delineation of isthmus ablation lesions in patients with typical atrial flutter.
Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125 - DOI: 10.1161/CIRCIMAGING.110.957670

Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robbins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R

Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography.
Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499

Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R

Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury: reply.
World J Surg. 2011;35(3):694-5 - PMID: 20645091 - DOI: 10.1007/s00268-010-0728-5

Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG

Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models.
PLoS One. 2010;5(4):e10032 - PMID: 20386609 - PMCID: PMC2850367 - DOI: 10.1371/journal.pone.0010032

Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M

Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction.
Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104 - DOI: 10.1161/CIRCRESAHA.110.227454

Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M

Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice.
J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607 - DOI: 10.1172/JCI42304

Libby P, Nahrendorf M, Weissleder R

Molecular imaging of atherosclerosis: a progress report.
Tex Heart Inst J. 2010;37(3):324-7 - PMID: 20548813 - PMCID: PMC2879214

Nahrendorf M, Pittet MJ, Swirski FK

Monocytes: protagonists of infarct inflammation and repair after myocardial infarction.
Circulation. 2010;121(22):2437-45 - PMID: 20530020 - PMCID: PMC2892474 - DOI: 10.1161/CIRCULATIONAHA.109.916346

Lee DK, Nahrendorf M, Schellingerhout D, Kim DE

Will molecular optical imaging have clinically important roles in stroke management, and how?
J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295 - DOI: 10.3988/jcn.2010.6.1.10

Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R

Hybrid PET-optical imaging using targeted probes.
Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107

Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089

Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R

Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury.
World J Surg. 2010;34(2):336-43 - PMID: 20033407 - PMCID: PMC2809822 - DOI: 10.1007/s00268-009-0332-8

Vinegoni C, Fexon L, Feruglio PF, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R

High throughput transmission optical projection tomography using low cost graphics processing unit.
Opt Express. 2009;17(25):22320-32 - PMID: 20052155 - PMCID: PMC2805020 - DOI: 10.1364/OE.17.022320

Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A

Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.
Circ Cardiovasc Imaging. 2009;2(6):468-75 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779

Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L

Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-7 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678

Matter CM, Stuber M, Nahrendorf M

Imaging of the unstable plaque: how far have we got?
Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148 - DOI: 10.1093/eurheartj/ehp419

Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R

18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis.
JACC Cardiovasc Imaging. 2009;2(10):1213-22 - PMID: 19833312 - PMCID: PMC2773129 - DOI: 10.1016/j.jcmg.2009.04.016

Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA

Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation.
J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u

Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ

Identification of splenic reservoir monocytes and their deployment to inflammatory sites.
Science. 2009;325(5940):612-6 - PMID: 19644120 - PMCID: PMC2803111 - DOI: 10.1126/science.1175202

Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R

Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086

Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O

Feasibility of real-time MRI with a novel carbon catheter for interventional electrophysiology.
Circ Arrhythm Electrophysiol. 2009;2(3):258-67 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357

Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R

MRI of a novel murine working heart transplant model.
Circ Heart Fail. 2009;2(3):272-4 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707

Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski FK

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.
PLoS One. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949 - DOI: 10.1371/journal.pone.0005663

Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R

Born normalization for fluorescence optical projection tomography for whole heart imaging.
J Vis Exp. 2009;(28):ePub - PMID: 19578329 - PMCID: PMC2794886 - DOI: 10.3791/1389

Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton AP, Waterman P, Figueiredo JL, Kohler RH, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle.
Neoplasia. 2009;11(5):459-68, 2 p following 468 - PMID: 19412430 - PMCID: PMC2672160 - DOI: 10.1593/neo.09356

Christen T, Nahrendorf M, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P

Molecular imaging of innate immune cell function in transplant rejection.
Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888

Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R

Normalized Born ratio for fluorescence optical projection tomography.
Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918 - DOI: 10.1364/ol.34.000319

Kelly KA, Shaw SY, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R

Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.
Integr Biol (Camb). 2009;1(4):311-7 - PMID: 20023731 - PMCID: PMC2748356 - DOI: 10.1039/b821775k

Nahrendorf M, Sosnovik DE, French BA, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ

Multimodality cardiovascular molecular imaging, Part II.
Circ Cardiovasc Imaging. 2009;2(1):56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092

Devaraj NK, Keliher EJ, Thurber GM, Nahrendorf M, Weissleder R

18F labeled nanoparticles for in vivo PET-CT imaging.
Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737 - DOI: 10.1021/bc8004649

Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA, Gropler RJ

Multimodality cardiovascular molecular imaging, part I.
Circ Cardiovasc Imaging. 2008;1(3):244-56 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359

Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ

Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation.
J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705 - DOI: 10.1172/JCI36335

Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne SW, Blankesteijn WM, Sosnovik DE, Jaffer FA, Tung CH, Weissleder R

Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.
Eur Heart J. 2008;29(4):445-54 - PMID: 18276618 - DOI: 10.1093/eurheartj/ehm558

Sosnovik DE, Nahrendorf M, Weissleder R

Targeted imaging of myocardial damage.
Nat Clin Pract Cardiovasc Med. 2008;5 Suppl 2(Suppl 2):S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115

Libby P, Nahrendorf M, Pittet MJ, Swirski FK

Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal.
Circulation. 2008;117(25):3168-70 - PMID: 18574058 - DOI: 10.1161/CIRCULATIONAHA.108.783068

Nahrendorf M, Sosnovik DE, Weissleder R

MR-optical imaging of cardiovascular molecular targets.
Basic Res Cardiol. 2008;103(2):87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2

Sosnovik DE, Nahrendorf M, Weissleder R

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7

Nahrendorf M, Sosnovik D, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R

Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.
Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510

Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R

Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.
J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729 - DOI: 10.1002/jmri.20966

Wei CL, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA

Volume catheter parallel conductance varies between end-systole and end-diastole.
IEEE Trans Biomed Eng. 2007;54(8):1480-9 - PMID: 17694869 - DOI: 10.1109/TBME.2007.890732

Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885

Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik DE, Aikawa E, Libby P, Swirski FK, Weissleder R

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.
Circulation. 2007;117(3):379-87 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181

Aikawa E, Nahrendorf M, Figueiredo JL, Swirski FK, Shtatland T, Kohler RH, Jaffer FA, Aikawa M, Weissleder R

Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo.
Circulation. 2007;116(24):2841-50 - PMID: 18040026 - DOI: 10.1161/CIRCULATIONAHA.107.732867

Pittet MJ, Grimm J, Berger CR, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski FK, Weissleder R

In vivo imaging of T cell delivery to tumors after adoptive transfer therapy.
Proc Natl Acad Sci U S A. 2007;104(30):12457-61 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104

Sosnovik DE, Nahrendorf M, Weissleder R

Molecular magnetic resonance imaging in cardiovascular medicine.
Circulation. 2007;115(15):2076-86 - PMID: 17438163 - DOI: 10.1161/CIRCULATIONAHA.106.658930

Nahrendorf M, Sosnovik DE, Waterman P, Swirski FK, Pande AN, Aikawa E, Figueiredo JL, Pittet MJ, Weissleder R

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.
Circ Res. 2007;100(8):1218-25 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31

Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V

Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo.
Circulation. 2007;115(11):1384-91 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351

Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R

High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CT.
Am J Physiol Heart Circ Physiol. 2007;292(6):H3172-8 - PMID: 17322414 - PMCID: PMC2680216 - DOI: 10.1152/ajpheart.01307.2006

Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R

Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease.
Circulation. 2007;115(3):377-86 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913

Nahrendorf M, Weissleder R

[Advances in cardiovascular medicine through molecular imaging].
Radiologe. 2007;47(1):18-24 - PMID: 17187263 - DOI: 10.1007/s00117-006-1450-z

Nahrendorf M, Streif JU, Hiller KH, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob PM, Ertl G, Spindler M, Bauer WR

Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.
Am J Physiol Heart Circ Physiol. 2006;290(6):H2516-21 - PMID: 16415075 - DOI: 10.1152/ajpheart.01038.2005

Hiller KH, Waller C, Nahrendorf M, Bauer WR, Jakob PM

Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging.
Mol Imaging. 2006;5(2):115-21 - PMID: 16954025

Nahrendorf M, Weissleder R, Ertl G

Does FXIII deficiency impair wound healing after myocardial infarction?
PLoS One. 2006;1(1):e48 - PMID: 17183677 - PMCID: PMC1762326 - DOI: 10.1371/journal.pone.0000048

Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R

Molecular imaging of myocardial infarction.
J Mol Cell Cardiol. 2006;41(6):921-33 - PMID: 17067633 - DOI: 10.1016/j.yjmcc.2006.09.008

Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
Circulation. 2006;114(14):1504-11 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380

Jaffer FA, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R

Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials.
Mol Imaging. 2006;5(2):85-92 - PMID: 16954022

Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R

In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging.
Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746 - DOI: 10.1007/s11307-006-0043-6

Nahrendorf M, Hu K, Frantz S, Jaffer FA, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlöhner S, Novikov M, Dickneite G, Reed GL, Jakob P, Rosenzweig A, Bauer WR, Weissleder R, Ertl G

Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction.
Circulation. 2006;113(9):1196-202 - PMID: 16505171 - PMCID: PMC4066325 - DOI: 10.1161/CIRCULATIONAHA.105.602094

Pelzer T, Jazbutyte V, Hu K, Segerer S, Nahrendorf M, Nordbeck P, Bonz AW, Muck J, Fritzemeier KH, Hegele-Hartung C, Ertl G, Neyses L

The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats.
Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203 - DOI: 10.1016/j.cardiores.2005.04.035

Nahrendorf M, Spindler M, Hu K, Bauer L, Ritter O, Nordbeck P, Quaschning T, Hiller KH, Wallis J, Ertl G, Bauer WR, Neubauer S

Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction.
Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481 - DOI: 10.1016/j.cardiores.2004.10.006

Streif JU, Nahrendorf M, Hiller KH, Waller C, Wiesmann F, Rommel E, Haase A, Bauer WR

In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging.
Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416 - DOI: 10.1002/mrm.20327

Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle.
Magn Reson Med. 2005;54(3):718-24 - PMID: 16086367 - DOI: 10.1002/mrm.20617

Nahrendorf M, Hiller KH, Hu K, Zeijlemaker V, Griswold M, Bauer WR

Pacing in high field cardiac magnetic resonance imaging:
Pacing Clin Electrophysiol. 2004;27(5):671-4 - PMID: 15125728 - DOI: 10.1111/j.1540-8159.2004.00506.x

Wiesmann F, Herold V, Streiff JU, Nahrendorf M, Neubauer S, Rommel E, Haase A

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping.
Int J Cardiovasc Imaging. 2004;20(4):289-91 - PMID: 15529911 - DOI: 10.1023/b:caim.0000041945.64887.f4

Neuberger T, Greiser A, Nahrendorf M, Jakob PM, Faber C, Webb AG

23Na microscopy of the mouse heart in vivo using density-weighted chemical shift imaging.
MAGMA. 2004;17(3-6):196-200 - PMID: 15580377 - DOI: 10.1007/s10334-004-0048-6

Streif JU, Hiller KH, Waller C, Nahrendorf M, Wiesmann F, Bauer WR, Rommel E, Haase A

In vivo assessment of absolute perfusion in the murine skeletal muscle with spin labeling MRI. Magnetic resonance imaging.
J Magn Reson Imaging. 2003;17(1):147-52 - PMID: 12500285 - DOI: 10.1002/jmri.10229

Streif JU, Herold V, Szimtenings M, Lanz TE, Nahrendorf M, Wiesmann F, Rommel E, Haase A

In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI.
Magn Reson Med. 2003;49(2):315-21 - PMID: 12541252 - DOI: 10.1002/mrm.10342

Waller C, Hiller KH, Albrecht M, Hu K, Nahrendorf M, Gattenlöhner S, Haase A, Ertl G, Bauer WR

Microvascular adaptation to coronary stenosis in the rat heart in vivo: a serial magnetic resonance imaging study.
Microvasc Res. 2003;66(3):173-82 - PMID: 14609522 - DOI: 10.1016/s0026-2862(03)00058-x

Nahrendorf M, Frantz S, Hu K, von zur Mühlen C, Tomaszewski M, Scheuermann H, Kaiser R, Jazbutyte V, Beer S, Bauer W, Neubauer S, Ertl G, Allolio B, Callies F

Effect of testosterone on post-myocardial infarction remodeling and function.
Cardiovasc Res. 2003;57(2):370-8 - PMID: 12566109 - DOI: 10.1016/s0008-6363(02)00701-0

Nahrendorf M, Hiller KH, Greiser A, Kohler S, Neuberger T, Hu K, Waller C, Albrecht M, Neubauer S, Haase A, Ertl G, Bauer WR

Chronic coronary artery stenosis induces impaired function of remote myocardium: MRI and spectroscopy study in rat.
Am J Physiol Heart Circ Physiol. 2003;285(6):H2712-21 - PMID: 12933339 - DOI: 10.1152/ajpheart.00233.2003

Nahrendorf M, Hiller KH, Hu K, Ertl G, Haase A, Bauer WR

Cardiac magnetic resonance imaging in small animal models of human heart failure.
Med Image Anal. 2003;7(3):369-75 - PMID: 12946475 - DOI: 10.1016/s1361-8415(03)00011-2

Nahrendorf M, Hiller KH, Theisen D, Hu K, Waller C, Kaiser R, Haase A, Ertl G, Brinkmann R, Bauer WR

Effect of transmyocardial laser revascularization on myocardial perfusion and left ventricular remodeling after myocardial infarction in rats.
Radiology. 2002;225(2):487-93 - PMID: 12409584 - DOI: 10.1148/radiol.2252011325

Nahrendorf M, Hu K, Hiller KH, Galuppo P, Fraccarollo D, Schweizer G, Haase A, Ertl G, Bauer WR, Bauersachs J

Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study.
J Am Coll Cardiol. 2002;40(9):1695-700 - PMID: 12427425 - DOI: 10.1016/s0735-1097(02)02375-6

Nahrendorf M, Hu K, Fraccarollo D, Hiller KH, Haase A, Bauer WR, Ertl G

Time course of right ventricular remodeling in rats with experimental myocardial infarction.
Am J Physiol Heart Circ Physiol. 2002;284(1):H241-8 - PMID: 12388245 - DOI: 10.1152/ajpheart.00537.2002

Waller C, Hiller KH, Kahler E, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR

Serial magnetic resonance imaging of microvascular remodeling in the infarcted rat heart.
Circulation. 2001;103(11):1564-9 - PMID: 11257086 - DOI: 10.1161/01.cir.103.11.1564

Nahrendorf M, Wiesmann F, Hiller KH, Hu K, Waller C, Ruff J, Lanz TE, Neubauer S, Haase A, Ertl G, Bauer WR

Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats.
J Magn Reson Imaging. 2001;14(5):547-55 - PMID: 11747006 - DOI: 10.1002/jmri.1218

Waller C, Kahler E, Hiller KH, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR

Myocardial perfusion and intracapillary blood volume in rats at rest and with coronary dilatation: MR imaging in vivo with use of a spin-labeling technique.
Radiology. 2000;215(1):189-97 - PMID: 10751486 - DOI: 10.1148/radiology.215.1.r00ap07189

Nahrendorf M, Wiesmann F, Hiller KH, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer WR

In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging.
J Cardiovasc Magn Reson. 2000;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565

Hu K, Gaudron P, Anders HJ, Weidemann F, Turschner O, Nahrendorf M, Ertl G

Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin.
Cardiovasc Res. 1998;39(2):401-12 - PMID: 9798525 - DOI: 10.1016/s0008-6363(98)00090-x
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