Huse C, Murphy SL, Yang K, Balzer NR, Stokke MK, Anstensrud AK, Bjerkeli V, Rentz T, Jha PK, Ugland HK, Michelsen AE, Ueland T, Holm S, Tøllefsen IM, Bendz B, Kleveland O, Andersen GØ, Gullestad L, Louch WE, Woxholt S, Osnes L, Broch K, Ulas T, Aukrust P, Libby P, Halvorsen B, Dahl TB

The effects of interleukin-6-receptor inhibition on monocytes in STEMI: a substudy of the ASSAIL-MI trial.
EBioMedicine. 2025;121:105960 - PMID: 41076990 - PMCID: PMC12547449 - DOI: 10.1016/j.ebiom.2025.105960

Jang HJ, Kim J, Kim H, Kim T, Chung J, Cremer S, Krohn-Grimberghe M, Kim EJ, Schellingerhout D, Nahrendorf M, Kim DE

Inhibiting Monocyte Migration Reduces Arterial Thrombosis and Facilitates Thrombolysis.
Stroke. 2025;56(12):3438-3453 - PMID: 41070446 - PMCID: PMC12636086 - DOI: 10.1161/STROKEAHA.125.052352

Wei J, Zhao X, Woo J, Ouyang J, El Fakhri G, Chen Q, Liu X

Mixture-of-Shape-Experts (MoSE): End-to-End Shape Dictionary Framework to Prompt SAM for Generalizable Medical Segmentation.
Conf Comput Vis Pattern Recognit Workshops. 2025;2025:6450-6460 - PMID: 41069640 - PMCID: PMC12506896 - DOI: 10.1109/cvprw67362.2025.00642

Zide BS, Gagliardi G, Jacobs HIL, Gatchel JR, Quiroz YT, Marshall GA, Rentz DM, Johnson KA, Sperling RA, Vannini P, Donovan NJ, Harvard Aging Brain Study

Living Alone, Early Tau Pathology, and Loneliness in Cognitively Unimpaired Older Adults During the COVID-19 Pandemic.
Am J Geriatr Psychiatry. 2025;34(1):57-69 - PMID: 41107199 - PMCID: PMC12765498 - DOI: 10.1016/j.jagp.2025.09.014

Chiu N, Libby P

A New Bleeding Signal in Clonal Hematopoiesis-White Cells, Red Flags.
JAMA Cardiol. 2025;10(12):1235-1237 - PMID: 41091500 - DOI: 10.1001/jamacardio.2025.3744

Hall IF, Aikawa E, Sluimer J, Baker AH, Kovacic JC

Endothelial to mesenchymal transition in cardiovascular diseases: molecular insights and clinical perspectives.
Eur Heart J. 2025;:ePub - PMID: 41128016 - DOI: 10.1093/eurheartj/ehaf670

Albright CA, Fosco GM, Feinberg ME, Sloan CJ, Fang S

Family vulnerability, disruption, and parent mental health problems during the COVID-19 pandemic.
J Fam Psychol. 2025;40(1):49-60 - PMID: 41143775 - PMCID: PMC12614447 - DOI: 10.1037/fam0001411

Deanfield J, Lincoff AM, Kahn SE, Emerson SS, Lingvay I, Scirica BM, Plutzky J, Kushner RF, Colhoun HM, Hovingh GK, Stensen S, Weeke PE, Jeppesen OK, Bravo R, Wu CC, Komuro I, Santini F, Hjelmesæth J, Urina-Triana M, Buscemi S, Ryan DH

Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial.
Lancet. 2025;406(10516):2257-2268 - PMID: 41138739 - DOI: 10.1016/S0140-6736(25)01375-3

Kim H, Jutten RJ, Soberanes D, Dubbelman MA, D'Aquila L, Udeogu OJ, Marshall GA, Johnson KA, Rentz DM, Sperling RA, Papp KV, Amariglio RE

Using memory recall response time on digital cognitive testing to detect subtle cognitive changes among cognitively unimpaired older adults.
Alzheimers Dement. 2025;21(10):e70815 - PMID: 41152156 - PMCID: PMC12568383 - DOI: 10.1002/alz.70815

Nahrendorf M

Recognizing Early Career Translational Investigators.
JACC Basic Transl Sci. 2025;10(10):101398 - PMID: 41161898 - PMCID: PMC12665410 - DOI: 10.1016/j.jacbts.2025.101398

Ferreira AV, Nahrendorf M

Metabolic Memory Resides in the Hematopoietic Marrow and in Arterial Resident Leukocytes.
JACC Basic Transl Sci. 2025;10(10):101392 - PMID: 41161897 - PMCID: PMC12665419 - DOI: 10.1016/j.jacbts.2025.101392

Yau WW, Kirn DR, Rabin JS, Properzi MJ, Schultz AP, Shirzadi Z, Palmgren K, Matos P, Maa C, Pruzin JJ, Schultz SA, Buckley RF, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP

Physical activity as a modifiable risk factor in preclinical Alzheimer's disease.
Nat Med. 2025;31(12):4075-4083 - PMID: 41184638 - PMCID: PMC12705434 - DOI: 10.1038/s41591-025-03955-6

Yang F, Yu M, Yuan Y, Xu J, Liu M, Nie S, Xiong Y, Yu L, Long Q, Zhu Z, Zha L, Zhang J, Xie Q, Han X, Li X, Yang J, Yang K, He L, Chen M, Hu L, Hong L, Dou K, Lei Y, Yao W, Shan Z, Libby P, Wang X, Han Y, Yuan H, Cheng X

A new comprehensive parameter combining residual C-reactive protein and neutrophil risk predicting adverse events in Chinese patients after percutaneous coronary intervention: A multi-center prospective cohort study.
Chin Med J (Engl). 2025;139(1):139-141 - PMID: 41184210 - PMCID: PMC12768049 - DOI: 10.1097/CM9.0000000000003885

Ramos-Cejudo J, Beiser AS, Lu S, Tanner JA, Scott MR, He T, Ghosh S, Johnson KA, Salinas J, Bubu OM, Fieremans E, Convit A, Pomara N, Wisniewski T, Berger JS, Osorio RS, Decarli CS, Johnson AD, Seshadri S

Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study.
Neurology. 2025;105(10):e214314 - PMID: 41187307 - PMCID: PMC12596005 - DOI: 10.1212/WNL.0000000000214314

Xue L, Bhattacharya R, Uddin MM, Nakao T, Zou R, Patel A, Haidermota S, Niroula A, Viscosi V, Postupaka D, Bhatnagar A, Finneran P, Bernardo R, Diggs MR, Fitch KV, Chu SM, McCallum S, Currier JS, Fichtenbaum CJ, Malvestutto CD, Aberg JA, Bloomfield GS, Ribaudo HJ, Zanni MV, Libby P, Hornsby W, Lu MT, Douglas PS, Grinspoon SK, Natarajan P

Clonal Hematopoiesis and Major Adverse Cardiac Events in People With HIV: Insights From the REPRIEVE Trial.
Arterioscler Thromb Vasc Biol. 2025;46(1):168-177 - PMID: 41195533 - PMCID: PMC12765570 - DOI: 10.1161/ATVBAHA.125.322896

Flynn S, Schuermans A, Uddin MM, Nakao T, Viscosi V, Libby P, Natarajan P, Honigberg MC

Clonal Hematopoiesis and Incident Heart Failure.
JAMA Cardiol. 2025;:ePub - PMID: 41206888 - PMCID: PMC12598579 - DOI: 10.1001/jamacardio.2025.4603

Feinberg MW, Plutzky J

Flipping the PRDM16 switch in 'multifunctional mesenchymes' may help to define atherosclerotic plaque.
Nat Cardiovasc Res. 2025;4(11):1459-1461 - PMID: 41203911 - DOI: 10.1038/s44161-025-00743-w

Fu JF, Robinson T, Rodriguez Alonso M, Francis Malave A, Jutten RJ, Properzi MJ, Healy BC, Thompson JC, Del Carmen Montenegro G, Thibault E, Penney D, Davis R, Sperling RA, Papp KV, Johnson KA, Price JC, Rentz DM

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test.
Ann Clin Transl Neurol. 2025;:ePub - PMID: 41214447 - DOI: 10.1002/acn3.70233

Peña-Trujillo V, Gallo-Bernal S, Moran CJ, Cortes Albornoz NS, Menys A, Gee MS

Magnetic resonance imaging-based ileal motility quantification predicts stricture response to biologic therapy in Crohn's disease.
Pediatr Radiol. 2025;:ePub - PMID: 41219519 - DOI: 10.1007/s00247-025-06406-z

Jaffer FA, Dweck MR, Tearney GJ, Libby P, Tawakol A

Cellular and molecular imaging of coronary atherosclerosis: clinical applications.
Eur Heart J. 2025;:ePub - PMID: 41222955 - DOI: 10.1093/eurheartj/ehaf804

Saba L, Libby P

Carotid Artery Stenosis-An Impactful Bias in Ischemic Stroke Classification.
JAMA Cardiol. 2025;11(1):11-13 - PMID: 41222944 - DOI: 10.1001/jamacardio.2025.4206

Ning MH, Rodionov A, Ross JM, Ozdemir RA, Burch M, Lian SJ, Alsop D, Cavallari M, Dickerson B, Fong T, Jones RN, Libermann T, Marcantonio E, Santarnecchi E, Schmitt EM, Touroutoglou A, Travison T, Acker L, Smith MR, Sun H, Westover MB, Pascual-Leone Á, Berger M, Inouye SK, Shafi M

Prediction of postoperative delirium in older adults from preoperative cognition and occipital alpha power from resting-state electroencephalogram.
Age Ageing. 2025;54(11):ePub - PMID: 41222553 - DOI: 10.1093/ageing/afaf330

Bauer CM, Rabin JC, Harpster K

Editorial: Visual perception in children and adolescents with visual impairments.
Front Hum Neurosci. 2025;19:1713145 - PMID: 41234660 - PMCID: PMC12605123 - DOI: 10.3389/fnhum.2025.1713145

Usiskin IM, Weber BN, Qi Y, Zhong K, Jeffway M, Weinblatt ME, Shadick N, Plutzky J, Liao KP

Comparison of PREVENT with the pooled cohort equation for estimating atherosclerotic cardiovascular disease risk among patients with rheumatoid arthritis.
Am J Prev Cardiol. 2025;24:101338 - PMID: 41245987 - PMCID: PMC12615325 - DOI: 10.1016/j.ajpc.2025.101338

Ferraciolli SF, Gee MS, Drzewiecki B, Eklund M, Hartung EA, Khanna G, Morani AC, Smith EA, Back SJ

Imaging of Pediatric Renal Cysts: An Update-AJR Expert Panel Narrative Review.
AJR Am J Roentgenol. 2025;:ePub - PMID: 41258657 - DOI: 10.2214/AJR.25.33832

Yao J, Farrar CT, Aikawa E, Sosnovik DE, Moon BF, Kulkarni A, Ackerman JL

Ex Vivo Phosphorus-31 Solid State Magnetic Resonance Spectroscopy Identifies Compositional Differences Between Bone Mineral and Calcified Vascular Tissues.
medRxiv. 2025;:ePub - PMID: 41256110 - PMCID: PMC12622083 - DOI: 10.1101/2025.09.27.25336805

Mhamedi EC, Hubé F, Alahari SK, Enguita FJ, Pardini B, Feinberg MW, Poliseno L, Armanios B, Jin J, Zhong XB, Sideris N, Bayraktar S, Castellano L, Santulli G, Jankauskas SS, Plewa WS, Conn SJ, Yang L, Shiu PKT, Kaushik A, Serganov A, Gentile M, Viglietto G, Amodio N, Mitić T, Caporali A

The Non-Coding RNA Journal Club: Highlights on Recent Papers-14.
Noncoding RNA. 2025;11(6):ePub - PMID: 41283330 - PMCID: PMC12641628 - DOI: 10.3390/ncrna11060075

Mutarelli A, Pantaleao AN, Melo PHC, Nogueira W, Nogueira A, Felix N, Generoso G, Cardoso R, Lupieri A, Aikawa E, Levine RA, Nunes MCP

Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis.
Front Cardiovasc Med. 2025;12:1615158 - PMID: 41282342 - PMCID: PMC12631635 - DOI: 10.3389/fcvm.2025.1615158

Bueno G, Bot I, Kanhai AA, Stilhano R, Libby P, De Meyer GRY, Martin L

Mast cells in cardiovascular disease: Fibrosis, angiogenesis and atherogenesis.
Prog Cardiovasc Dis. 2025;:ePub - PMID: 41290054 - DOI: 10.1016/j.pcad.2025.11.007

Joodaki M, Rodgers G, Hopf A, Koller MR, Guzman R, Santarnecchi E, Vögerl JS, Ferchow J, Ruffner A, Funken M, Meboldt M, Osmani B

A patient-specific, 3D printed neurostimulator enabling focal transcranial electrical stimulation and EEG at home.
J Neuroeng Rehabil. 2025;22(1):248 - PMID: 41287086 - PMCID: PMC12642300 - DOI: 10.1186/s12984-025-01769-8

Nahrendorf M

Recognizing Early Career Translational Investigators.
JACC Basic Transl Sci. 2025;10(11):101410 - PMID: 41298046 - PMCID: PMC12790141 - DOI: 10.1016/j.jacbts.2025.101410

Nahrendorf M, Kumowski N, Steffens S

Neutrophils in Myocardial Infarction.
JACC Basic Transl Sci. 2025;10(11):101408 - PMID: 41298044 - PMCID: PMC12790144 - DOI: 10.1016/j.jacbts.2025.101408

Qin S, Xing F, Cho J, Park J, Liu X, Rouhollahi A, Farhat EJB, Javadikasgari H, Sabe A, Nezami FR, Woo J, Aganj I

Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer.
bioRxiv. 2025;:ePub - PMID: 41292924 - PMCID: PMC12642416 - DOI: 10.1101/2024.09.27.615510

Mendes Zambetta R, De Favari Signini É, Catai AM, Benelli A, Angius L, Dos Santos TCR, Michaliski ES, de Oliveira LB, Ocamoto GN, Santarnecchi E, Frigieri G, Russo TL

Effect of simulated microgravity via head-down tilt on intracranial compliance, brain oscillations and cardiovascular autonomic modulation.
Sci Rep. 2025;15(1):42316 - PMID: 41309788 - PMCID: PMC12660767 - DOI: 10.1038/s41598-025-26319-z

Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, NHLBI Trans-Omics for Precision Medicine, Libby P, Gupta RM, Natarajan P

Human plasma proteomic profile of clonal hematopoiesis.
Nat Commun. 2025;16(1):11688 - PMID: 41309676 - PMCID: PMC12748892 - DOI: 10.1038/s41467-025-66755-z

Aytuglu A, Graham-Engeland JE, Feinberg ME, Murray-Perdue SA, Conway CA, Schreier HMC

Longitudinal associations between father- and mother-child interactions, coparenting, and child cardiometabolic health.
Health Psychol. 2025;:ePub - PMID: 41325157 - PMCID: PMC12671923 - DOI: 10.1037/hea0001567

Annex BH, Bristow MR, Frangogiannis NG, Kelly DP, Kontaridis M, Libby P, MacLellan WR, McNamara CA, Mann DL, Pitt GS, Sipido KR

JACC: Basic to Translational Science: Honoring the Top Reviewers of 2024.
JACC Basic Transl Sci. 2025;10(1):129 - PMID: 41354477 - PMCID: PMC11830239 - DOI: 10.1016/j.jacbts.2024.12.001

Cantoni V, Casula EP, Tarantino B, Cupidi C, Huber N, Altomare D, Premi E, Zummo E, Esposito R, Leonardi C, Herukka SK, Solje E, Ferrari A, Cotelli MS, Gasparotti R, Martorana A, Fracassi C, Santarnecchi E, Koch G, Haapasalo A, Grassi M, Benussi A, Borroni B

Home-Based Gamma Transcranial Alternating Current Stimulation in Patients With Alzheimer Disease: A Randomized Clinical Trial.
JAMA Netw Open. 2025;8(12):e2546556 - PMID: 41359335 - PMCID: PMC12687098 - DOI: 10.1001/jamanetworkopen.2025.46556

van Dyck CH, Sperling R, Johnson K, Dhadda S, Kanekiyo M, Li D, Gee M, Hersch S, Irizarry M, Kramer L

Long-term safety and efficacy of lecanemab in early Alzheimer's disease: Results from the clarity AD open-label extension study.
Alzheimers Dement. 2025;21(12):e70905 - PMID: 41355080 - PMCID: PMC12682705 - DOI: 10.1002/alz.70905

Serrano CV, Ribeiro ML, Bichuette LD, Matuck BRS, Severino P, Gollob KJ, Lima JAC, Libby P

Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms.
Einstein (Sao Paulo). 2025;23:eRW1780 - PMID: 41370510 - PMCID: PMC12671654 - DOI: 10.31744/einstein_journal/2025RW1780

Kurt B, Reugels M, Schneider KM, Spiesshoefer J, Milzi A, Gombert A, Fordyce CB, Wenzl FA, Pagidipati NJ, Rocha V, Fudim M, Sharma A, Lehrke M, Shimokawa H, Liuzzo G, Tokgozoglu L, Crea F, Lüscher TF, Libby P, Ridker PM, Marx N, Schneider CV, Kahles F

C-reactive protein and cardiovascular risk in the general population.
Eur Heart J. 2025;:ePub - PMID: 41378999 - DOI: 10.1093/eurheartj/ehaf937

Aikawa M, Sonawane AR, Chelvanambi S, Asano T, Halu A, Matamalas JT, Singh SA, Uchida S, Aikawa E, Arenas A, Balligand JL, Giannarelli C, MacRae CA, Morgan NV, Oury C, Stahel HT, Loscalzo J

Precision cardiovascular medicine: shifting the innovation paradigm.
Front Sci. 2025;3:ePub - PMID: 41378166 - PMCID: PMC12687475 - DOI: 10.3389/fsci.2025.1474469

Meteva D, Pedicino D, Abdelwahed YS, Kränkel N, Anwari E, Leistner DM, den Ruijter H, Gerhardt T, Joner M, Libby P, Jang IK, Crea F, Landmesser U

Acute coronary syndrome with plaque erosion: clinical characteristics, mechanisms, and unmet needs.
Eur Heart J. 2025;:ePub - PMID: 41384362 - DOI: 10.1093/eurheartj/ehaf1004

Yao J, Farrar CT, Aikawa E, Sosnovik DE, Moon BF, Kulkarni A, Ackerman JL

Ex vivo phosphorus-31 solid state magnetic resonance spectroscopy identifies compositional differences between bone mineral and calcified vascular tissues.
Front Cardiovasc Med. 2025;12:1689116 - PMID: 41383646 - PMCID: PMC12689968 - DOI: 10.3389/fcvm.2025.1689116

Seto M, Klinger HM, Clifton M, Janve VA, Brown JA, Birkenbihl C, Coughlan G, Townsend DL, Wang TC, Properzi M, Hanseeuw B, Chhatwal J, Yang HS, Rissman RA, Aisen P, Cuppels M, Donohue MC, Raman R, Johnson KA, Sperling RA, Dumitrescu L, Hohman TJ, Buckley RF

Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease.
bioRxiv. 2025;:ePub - PMID: 41394556 - PMCID: PMC12697722 - DOI: 10.1101/2025.11.21.689770

Johnson K, Martin P, McGrail M

Interprofessional education and collaborative practice in diagnostic radiography: Insights from an Australian interview study.
Radiography (Lond). 2025;32(2):103285 - PMID: 41411806 - DOI: 10.1016/j.radi.2025.103285

Small AM, Yang TY, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K, Vy HMT, Farber-Eger EH, Shaffer LL, Boulier KM, Corey KM, Ramaker ME, Laporte F, Schott JJ, Le Scouarnec S, Singh SA, Sonawane AR, Smith HA, Rafaels N, Colorado Center for Personalized Medicine, Ghouse J, Raja AA, Ostrowski SR, Sørensen E, Mikkelsen C, Pedersen OB, Erikstrup C, Ullum H, DBDS Genomic Consortium, Sveinbjornsson G, Gudbjartsson DF, Abner E, Estonian Biobank Research Team, Lee J, Ganna A, Nowak-Göttl U, Finer S, Genes & Health Research Team, Schumacher J, Maj C, Al-Kassou B, Nickenig G, Trenkwalder T, Dreβen M, Krane M, Nöthen MM, Moksnes MR, Brumpton BM, Knight S, Knowlton KU, Nadauld L, Debiec R, Musameh MD, Braund PS, Nelson CP, Czuba T, Melander O, Selvaraj MS, Koyama S, Bhukar R, Ruan Y, Ljungberg J, Damrauer SM, Levin MG, Franke A, Berger K, Ruff CT, Melloni GEM, Kamanu FK, Ito K, Do R, Loos RJF, Schunkert H, Wells QS, Shah SH, Le Tourneau T, Messika-Zeitoun D, Gignoux C, Bundgaard H, Larsson SC, Michaëlsson K, Holm H, Helgadottir A, Esko T, van Heel DA, Mathieu P, Samani NJ, Smith JG, Söderberg S, Rader DJ, Marston NA, Sabatine MS, Pasaniuc B, Cho K, Wilson PWF, O'Donnell CJ, Stefansson K, Bossé Y, Aikawa E, Engert JC, Peloso GM, Natarajan P, Thanassoulis G

Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.
Nat Genet. 2025;58(1):57-66 - PMID: 41419686 - PMCID: PMC12807872 - DOI: 10.1038/s41588-025-02417-6

Li Z, Shi Y, Wang L, Lu J, Liu X, Woo J, Ouyang J, Hu J, Zhou D, Gong W, Yang X, Yu H, Wang Y, Liu F, Dong Y, Ye M, Shi S, Chen X, Qiu M, El Fakhri G, Kong L, Sun X, Zheng Y, Shi Y, Yu H, Liu X

Deep learning-based non-contrast MRI model for nasopharyngeal carcinoma diagnosis: an end-to-end gadolinium-free solution.
NPJ Digit Med. 2025;8(1):786 - PMID: 41430426 - PMCID: PMC12748797 - DOI: 10.1038/s41746-025-02247-0

Fogacci F, Libby P, Cicero AFG

Lipoprotein(a)-To test or not to test, not a dilemma but a mandate.
J Clin Lipidol. 2025;19(6):1520-1522 - PMID: 41429468 - DOI: 10.1016/j.jacl.2025.09.030

Najmaoui Y, Chemli Y, Toussaint M, Petibon Y, Marty B, Fontaine K, Gallezot JD, Razdevšek G, Orehar M, Dhaynaut M, Guehl N, Dolenec R, Pestotnik R, Johnson K, Ouyang J, Normandin M, Tétrault MA, Lecomte R, El Fakhri G, Marin T

YRT-PET: An Open-Source GPU-accelerated Image Reconstruction Engine for Positron Emission Tomography.
IEEE Trans Radiat Plasma Med Sci. 2025;:ePub - PMID: 41424471 - PMCID: PMC12714321 - DOI: 10.1109/TRPMS.2025.3619872
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